CBD and the Brain: How CBD Can Help With TBIs
Posted: Apr 19, 2023
March is Brain Injury Awareness Month, a time when we raise awareness about the effects of traumatic brain injuries (TBIs) on individuals, families, and communities. TBIs can result from various incidents, such as car accidents, sports injuries, falls, and military combat. They can have long-lasting consequences, including cognitive impairment, memory loss, and emotional disturbances.
Research has shown that CBD, a non-intoxicating compound found in hemp, may be a promising option for TBI sufferers. CBD interacts with the body’s Endocannabinoid system, which regulates various physiological functions, including brain function. Here are some of the ways CBD may help TBIs.
- Anti-inflammatory properties
Inflammation in the brain is a common result of traumatic brain injuries, and it can lead to further damage and cognitive decline. CBD has been shown to reduce inflammation in the brain, which may help mitigate the damage caused by TBIs. Inflammation is the body’s response to injury or infection, and it’s a natural part of the healing process. However, when inflammation becomes chronic, it can be harmful and lead to various health issues.
Studies have shown that CBD can help reduce inflammation in the brain by interacting with the body’s Endocannabinoid system. The Endocannabinoid system is a complex network of receptors and molecules that help regulate various physiological functions, including inflammation. CBD activates certain receptors in the Endocannabinoid system, and acts as an antioxidant and neuroprotectant, which can help reduce inflammation in the brain.
CBD’s anti-inflammatory properties may also benefit other conditions that affect the brain, such as Alzheimer’s disease and multiple sclerosis.
- Neuroprotective effects
Neuroprotection is an essential component of TBI treatment, as it aims to prevent further damage to the brain after an injury has occurred. CBD has been shown to have neuroprotective effects, which may help prevent further damage to the brain and support the recovery process.
Studies have shown that CBD can protect brain cells from damage and death caused by various factors, including oxidative stress, inflammation, and excitotoxicity. Oxidative stress occurs when there is an imbalance between the production of free radicals and the body’s ability to neutralize them. Free radicals are unstable molecules that can damage cells and DNA, and they are produced naturally during the body’s metabolic processes. However, environmental factors such as pollution and radiation can also increase the production of free radicals. CBD has been shown to have antioxidant properties, which can help neutralize free radicals and protect brain cells from damage.
Excitotoxicity is another factor that can lead to brain cell death after a TBI. Excitotoxicity occurs when brain cells are overstimulated by neurotransmitters such as glutamate. This can lead to an influx of calcium ions into the cells, which can cause cell death. CBD has been shown to have anti-excitotoxic effects, which may help prevent this type of damage to the brain.
In addition to its neuroprotective effects, CBD may also stimulate the growth and development of new brain cells, a process known as neurogenesis. Neurogenesis is important for the brain’s ability to repair and regenerate after injury. A study published in the Journal of Clinical Investigation found that CBD can stimulate the formation of new brain cells in the hippocampus, a brain region involved in learning and memory.
Furthermore, CBD has been shown to improve blood flow to the brain, which is essential for brain function and recovery after a TBI. A study published in the Journal of Cerebral Blood Flow and Metabolism found that CBD can increase cerebral blood flow and improve oxygenation in the brain.
- Pain relief
Pain is a common symptom of TBIs, and it can be challenging to manage with traditional pain medications due to their potential side effects and addictive properties. CBD has been shown to have analgesic properties, which may help alleviate pain associated with TBIs.
CBD interacts with the body’s Endocannabinoid system, which affects pain sensation and perception. CBD indirectly binds to receptors in the Endocannabinoid system, which can help reduce pain and inflammation throughout the body.
CBD may also benefit headaches and migraines, which are common after TBIs. A study published in the Journal of Headache and Pain found that CBD can reduce the frequency and severity of migraines in people who suffer from them.
- Anxiety and Depression
Anxiety and depression are common comorbidities of TBIs, and they can significantly impact a person’s quality of life and recovery process. CBD has been shown to have anxiolytic and antidepressant effects, which may help alleviate symptoms of anxiety and depression in people who have suffered a TBI.
CBD’s anxiolytic and antidepressant effects may be due to its ability to interact with serotonin receptors in the brain. Serotonin is a neurotransmitter that regulates mood, and low serotonin levels have been linked to depression and anxiety disorders. CBD can enhance the activity of serotonin receptors, which can help improve mood and reduce symptoms of anxiety and depression.
Sleep is a critical aspect of the recovery process after a TBI, but it can be challenging to achieve due to pain, anxiety, and other symptoms associated with TBIs. CBD has been shown to have sleep-inducing properties, which may help improve sleep quality and duration in people who have suffered a TBI.
CBD’s sleep-supporting properties are due to its ability to interact with the body’s Endocannabinoid system, which plays a role in sleep regulation. CBD can stimulate the Endocannabinoid system, which can help regulate sleep-wake cycles and improve sleep quality.
It’s important to note that CBD should not be considered a cure for TBIs, and more research is needed to understand its effects on brain injuries fully. However, the existing research suggests that CBD may be a promising option.
If you or a loved one has experienced a TBI, it’s important to speak with a healthcare professional to determine the best course of treatment. CBD may be a complementary treatment option to consider alongside traditional therapies.
At Pure Spectrum, we offer many high-quality CBD products that may benefit TBI patients. Our products are rigorously tested for purity and potency, ensuring you get the best possible CBD experience. Whether you’re looking for oils, softgels, or gummies, we have something for everyone.
- Campos, A. C., Fogaça, M. V., Sonego, A. B., & Guimarães, F. S. (2016). Cannabidiol, neuroprotection and neuropsychiatric disorders. Pharmacological research, 112, 119-127.
- Mechoulam, R., Peters, M., Murillo-Rodriguez, E., & Hanus, L. O. (2007). Cannabidiol–recent advances. Chemistry & biodiversity, 4(8), 1678-1692.
- Russo, E. B. (2011). Taming THC: potential cannabis synergy and phytocannabinoid-terpenoid entourage effects. British journal of pharmacology, 163(7), 1344-1364.
- Wang, Y., Wu, C., Han, J., Huang, Y., & Yan, X. (2019). Involvement of the endocannabinoid system in regulating the neuronal response to acute and chronic inflammation in the central nervous system. Experimental neurology, 320, 112964.
- Zuardi, A. W., & Guimarães, F. S. (2017). Cannabidiol as a potential treatment for anxiety disorders. Current opinion in psychiatry, 30(2), 83-90.
- Zuardi, A. W., Rodrigues, N. P., Silva, A. L., Bernardo, S. A., Hallak, J. E., Guimarães, F. S., & Crippa, J. A. (2017). Inverted U-shaped dose-response curve of the anxiolytic effect of cannabidiol during public speaking in real life. Frontiers in pharmacology, 8, 259.